Product ID:CYTOSINE-B-D-ARABINOFURANOSIDE HYDROCHLORID
MSDS Date:05/07/1990
FSC:6810
NIIN:00N020458
MSDS Number: BLVNR

Emergency Phone: 314-771-5765

Info Phone: 800-325-3010 OR 314-771-5750

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

CYTOSINE, 1-BETA-D-ARABINOFURANOSYL-, MONOHYDROCHLORIDE;

CAS: 69-74-9

RTECS: HA5500000

LD50 LC50 Mixture:NONE SPECIFIED BY MANUFACTURER.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE:HARMFUL IF SWALLOWED, INHALED OR
ABSORBED THROUGH SKIN. CAUSES EYE & SKIN IRRIT. MATL IS IRRITATING
TO MUC MEMB & UPPER RESP TRACT. MAY CAUSE ALLERGIC SKIN RXN. MAY
CAUSE NERV SYS DISTURB. CHRON IC:MAY CAUSE CONGENITAL MALFORMATION
INTHE FETUS. LAB EXPT HAVE SHOWN MUTAGENIC EFTS. TARGET (SEE EFTS
OF OVEREXP)
Explanation of Carcinogenicity:NOT RELEVANT.
Effects of Overexposure:HLTH HAZ:ORGANS:BONE MARROW & NERVES. TO THE
BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL & TOXICOLOGICAL
PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED. TOXIC SYMPS INCL
GI DISTRESS, NAUSEA, VOMIT ING, DIARRHEA, HEPATIC DYSFUNCTION,
FEVER, DERM, MYALGIA, BONE PAIN, MACULOPAPULAR RASH, CONJUNCTIVITIS
& MALAISE.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:EYE/SKIN:IMMEDIATELY FLUSH W/COPIOUS AMOUNTS OF WATER FOR AT
LEAST 15 MINS WHILE REMOVING CONTAMINATED CLOTHING & SHOES. ASSURE
ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS W/FINGERS.
WASH CONTAMINATED CLOTHING BEFORE REUSE. INHAL:REMOVE TO FRESH
AIR. IF NOT BREATHING, GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS
DIFFICULT, GIVE OXYGEN. CALL MD. INGEST:CALL MD IMMEDIATELY .

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER,
ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA & FULL
PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH/MSHA APPRVD RESPIRATOR, CHEMICAL
SAFETY GOGGLES, RUBBER BOOTS & HEAVY RUBBER GLOVES. SWEEP UP, PLACE
IN A BAG & HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE
AREA & WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:REFRIGERATE. KEEP TIGHTLY CLOSED. DO
NOT BREATHE DUST. DO NOT GET IN EYES, ON SKIN OR ON CLOTHING. AVOID
PROLONGED OR REPEATED EXPOSURE.
Other Precautions:TERATOGEN. SENSITIZER. NEUROLOGICAL HAZARD. POSSIBLE
MUTAGEN. IRRITANT.

Respiratory Protection:WEAR APPROPRIATE NIOSH/MSHA APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:SAFETY SHOWER & EYE BATH. OTHER PROTECTIVE
CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
NONE SPECIFIED BY MANUFACTURER.

HCC:N1
Melt/Freeze Pt:M.P/F.P Text:387F,197C
Appearance and Odor:WHITE POWDER.

STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:NONE SPECIFIED BY MANUFACTURER.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE, NOX & HYDROGEN CHLORIDE GAS.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL W/A COMBUSTIBLE
SOLVENT & BURN IN A CHEMICAL INCINERATOR EQUIPPED W/AN AFTERBURNER
& SCRUBBER. OBSERVE ALL FEDERAL, STATE & LOCAL LAWS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.